منابع مشابه
Regulation of cellular iron metabolism
Iron is an essential but potentially hazardous biometal. Mammalian cells require sufficient amounts of iron to satisfy metabolic needs or to accomplish specialized functions. Iron is delivered to tissues by circulating transferrin, a transporter that captures iron released into the plasma mainly from intestinal enterocytes or reticuloendothelial macrophages. The binding of iron-laden transferri...
متن کاملCellular iron homeostasis and metabolism in plant
1 Dipartimento di Scienze Agrarie e Ambientali-Produzione, Territorio e Agroenergia, Università degli Studi di Milano, Milano, Italy 2 Center for Sustainable Resource Sciences, RIKEN Yokohama campus, RIKEN, Yokohama, Japan 3 Department Biology I-Plant Biochemistry and Physiology, Ludwig-Maximilians-University Munich, Munich, Germany 4 Biochimie and Physiologie Moléculaire des Plantes, Centre Na...
متن کاملCellular Iron Metabolism – The IRP/IRE Regulatory Network
Iron is the most abundant transition metal in cellular systems and is an essential micronutrient required for many cellular processes including DNA synthesis, oxidative cell metabolism, haemoglobin synthesis and cell respiration. Despite iron being an absolute requirement for almost all organisms, caution should be taken with an inappropriate disequilibrium in iron levels because excess iron is...
متن کاملThe effect of chelating agents on cellular iron metabolism.
1. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron uptake by the cells but had little effect on ferritin synthesis. Diethylenetriamine pentaacetic acid produced complete inhibition of iron upt...
متن کاملAlginate-Iron Speciation and Its Effect on In Vitro Cellular Iron Metabolism
Alginates are a class of biopolymers with known iron binding properties which are routinely used in the fabrication of iron-oxide nanoparticles. In addition, alginates have been implicated in influencing human iron absorption. However, the synthesis of iron oxide nanoparticles employs non-physiological pH conditions and whether nanoparticle formation in vivo is responsible for influencing cellu...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1999
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.1999.055suppl.69002.x